Outbreak of Serogroup W135 Meningococcal Disease after the Hajj Pilgrimage, Europe, 2000

نویسندگان

  • Jean-François Aguilera
  • Anne Perrocheau
  • Christine Meffre
  • Susan Hahné
چکیده

The 2000 Hajj (March 15-18) was followed by an outbreak of Neisseria meningitidis W135 2a: P1.2,5 in Europe. From March 18 to July 31, 2000, some 90 cases of meningococcal infection were reported from nine countries, mostly the United Kingdom (UK) and France; 14 cases were fatal. Although most early cases were in pilgrims, the outbreak spread to their contacts and then to those with no known pilgrim contact. In France and the UK, the outbreak case-fatality rate was compared with the rate reported from national surveillance. The risk of dying during this outbreak was higher in France and the UK, although the difference was not statistically significant. Prophylaxis for all pilgrims and their household contacts was offered in France; in the UK and other European countries, prophylaxis was recommended only for close contacts. No difference in transmission rates following intervention was detected between France and the UK.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Neisseria meningitidis Serogroup W 135 , China

To the Editor: Neisseria meningitidis is a gram-negative bacterium found only in humans and is a major cause of serious invasive diseases. Before 2006, in the People’s Republic of China, all meningococcal diseases were caused by serogroups A, B, and C. However, there are >13 serogroups of this organism. Three cases of infection with N. meningitidis serogroup W135 were reported in China during 2...

متن کامل

Extrameningeal complications of Neisseria meningitidis serogroup W135 infection.

Received 3 March 2004; accepted 4 March 2004; electronically published 12 May 2004. Reprints or correspondence: Dr. Michael A. Apicella, Dept. of Microbiology, University of Iowa, 51 Newton Rd., Iowa City, IA 52242 ([email protected]). Clinical Infectious Diseases 2004; 38:1638–9 2004 by the Infectious Diseases Society of America. All rights reserved. 1058-4838/2004/3811-0023$15.00 Nei...

متن کامل

Comparison of serogroup W-135 meningococci isolated in Sweden during a 23-year period and those associated with a recent hajj pilgrimage.

An outbreak of serogroup W-135 meningococcal disease was reported among pilgrims returning from the annual hajj (pilgrimage to Mecca) in mid-March 2000. Molecular characterization was used to investigate the similarity of the hajj-associated W-135 strains with those isolated in Sweden during a 23-year period (1978 to 2000). The same hajj-associated genosubtype, genosubtype P1.5,2,36b, has been ...

متن کامل

Persistence of W135 Neisseria meningitidis Carriage in Returning Hajj Pilgrims: Risk for Early and Late Transmission to Household Contacts

After an outbreak of meningococcal disease caused by Neisseria meningitidis W135, associated with the Hajj pilgrimage in 2001, 15% of returning vaccinated pilgrims carried a single W135 clone, and 55% were still carriers 6 months later. Transmission to 8% of their unvaccinated household contacts occurred within the first few weeks, but no late transmission took place. Public health intervention...

متن کامل

Neisseria meningitidis serogroup W135 isolates associated with the ET-37 complex.

To the Editor: As of April 20, 2000, >300 laboratory confirmed cases of meningococcal disease caused by N. meningitidis serogroup W135 (NMW135) have been reported in Saudi Arabia and nine other countries among Hajj pilgrims or their close contacts (1). This is the first reported multinational outbreak of W135 meningococcal disease. NMW135 accounts for <5% of meningococcal disease in the United ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره 8  شماره 

صفحات  -

تاریخ انتشار 2002